deanna529, please update us periodically on how Aficamten is working out for you. Please relay what you are feeling differently now that you are on week 24. At my last cardiologist visit, I asked about Mavacamten only because I was reading about it on this blog - so far I am doing fine after a septal myectomy. He said that in his experience, people generally eventually need surgery, which I know from reading was less than successful for you. My gradient was at least in the 60's when I started having issues, so Mavacamten was not recommended, it's now 0 or close to it. I do fear a regrowth/thickening of the ventricle wall, so far, so good.