Anyone have cancer with unknown primary?

I’m in the UK. I know they do the latest PIPAC in Germany and Spain. I think here too. There may be trials in US and I have no idea what the Mayo do. Sorry I can’t be of any more help.

No worries. They are doing trials at City of Hope in CA.

@tobydrake7, the team of Dr. Amit Merchea performed the first PIPAC in the USA on Dec 4th, 2019 at Mayo Clinic Jacksonville, FL.

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a promising and innovative method for treating peritoneal metastasis.

Here's a clinical trial that Dr. Merchea is conducting.
- A Safety to Evaluate the Safety and Effectiveness of Pressurized Intraperitoneal Aerosolized Chemotherapy in Ovarian, Uterine, Colorectal, and Gastric Cancer Patients https://www.mayo.edu/research/clinical-trials/cls-20517716

Thank you!

I filled out the online form to be considered for the clinical trial. Thanks again for this information.

Are you on clinical trial at MD Anderson?

Not yet. I am doing chemotherapy first to see if that takes care of it. If not, HIPEC or PIPEC may be an option, with either MD Anderson and/or Mayo Clinic. We’ll see.

Yes within the last month. The biopsy indicate renal cell carcinoma. However, the MRI shows no Tumors.

Hi @tom0329, where was the biopsy taken from? Did you have a mass or tumor outside of the kidney?

I've been diagnosed with Cancer unknown primary.
In January my dental hygienist found a small lump, at the time, in my left neck. After CT scans, biopsy it was confirmed carcinoma, highly undifferentiated. Pet scan showed tonsils and back of tongue being lit. Tonsillectomy was performed but negative for cancer. Had neck dissection to remove golf ball sized tumour from my neck. Histology is adenocarcinoma but pathology did not indicate primary.
I just started treatment-30 rounds of radiation and 3 rounds chemo/cisplatin.
My husband had throat cancer (voice box), fall 2022. He had a pet scan 11 months ago that was clean. Thencame thr devastating news. His cancer has returned and spread to both lungs with no option for surgery. We found this out 4 weeks ago. He has chemo/immunotherapy every 3 weeks. We are both going thru treatment.

Seems to me that scans should happen more frequently. In Canada, since Healthcare is free, this was detrimental.

Assume CUP cancers should do pet scans 3 months or 6 months? Anyone know the recommended guidelines? I would pay and travel to states if it means chance of catching it early/ living. My PET was in April.