I just received results of the CTX and P1NP blood tests and promised to post when received.

Quick background. Took 2 Prolia injections in 2022. Had very good results with the DEXA score in May 2023 so my PCP said I could quit Prolia. Yea. BUT he expected me to quit COLD TURKEY and was not aware of the need for any relay drug.

I sent him a study about needing a bisphonate to lock in Prolia gains and prevent fracture associated with stopping Prolia. He actually read the study and ordered Fosomax. I have had no side effects since starting it a year ago.

I had no previous BTM tests....so no baseline. At my doctor appointment on May 3rd, we discussed how long I should continue to take Fosomax and I requested the BTM tests. I also told him I was thinking to continue Fosomax for 18 months (which is 24 months from the last Prolia injection.)

He reluctantly agreed to order the tests as he does not think they are particularly helpful; there was also an insurance coverage snag that I hope has been straightened out.

Here are my results: CTX 313; P1NP 31.6. After fasting and early morning blood draw.

So do these results mean that I am losing bone a little faster than building bone but perhaps nothing really concerning as both are within the reference numbers. I have not yet discussed this with the doctor but do not expect him to be of any help in evaluating these results.

Hoping someone here might have some thoughts. I gather from discussions that it would be nice to see the CTX reach a target of 280. Or to see the ratio of the two tests be approximately 8:1. Can this happen on continued Fosomax use?

Thinking I would like the tests repeated in 6 months to see some sort of trend rather than a one-time snapshot.

Any thoughts appreciated.