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70 + year women with Thrombosis

Blood Cancers & Disorders | Last Active: May 14 1:08pm | Replies (17)

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@loribmt

Hi @rch552320 Your mom was recently diagnosed with thrombocytosis which is an excess of platelets in the blood. This can lead to concerns for blood clotting and strokes.
There can be underlying causes for this to take place so I’m wondering if your mother had further testing done by her doctor to determine the cause. It might be warranted to have a genetic test run to see if there is a mutation in the JAK2 gene.
In any event, Hydroxyurea, is generally the front line med to treat this condition to control the excess production of her platelets.
There are other medications for people who are not tolerant of HU if needed. Is your mom not doing tolerating the HU?

I found a conversation with other members who have Essential thrombocythemia and are taking either Jakafi, Anagrelide or Pegasus for ET management. Here’s a link to that discussion with @lynnevb and several others.

ET management, Is anyone here taking Jakafi or Pegasus?
https://connect.mayoclinic.org/discussion/et-management-is-anyone-here-taking-jakafi-or-pegasus/
Because you and your mom are new to this, I thought you might like to have a little more information about ET. Here are a couple of sites for you to investigate.
~From Verywellhealth.com
https://www.verywellhealth.com/essential-thrombocythemia-2860907
~~~~~~~
From Healthline.com https://www.healthline.com/health/primary-thrombocythemia

Is your mom having any side effects with taking Hydroxyurea?

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Replies to "Hi @rch552320 Your mom was recently diagnosed with thrombocytosis which is an excess of platelets in..."

Thank you Lori for your detailed guidance and explanation. HU currently she is taking one a day and two every alternative day. But her count in Feb 29, 2024 was around 988, but went up again in May May 9, 2024 -1185. Doctor has advised her to use two HU for a day. But mom complains about stomach upsets and has to drink plenty of water.....