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Letrozole and TMJ?

Breast Cancer | Last Active: Aug 5 2:48pm | Replies (18)

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@risagee

I, too, went through a serious recurrence of TMJ after being on Letrozole for about 3-4 months. At 6 months now — serious anxiety, insomnia, heart palpitations, and easily bruised skin. I feel fragile physically and emotionally…is this really worth it, I wonder..? Before BC, I was a reasonably fit and healthy 60 year old. Some days now I feel like I’m 80 🙁

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Replies to "I, too, went through a serious recurrence of TMJ after being on Letrozole for about 3-4..."

An oncologist told me that one third of breast cancer patients can’t tolerate aromatase inhibitors. Another third can stay on it, but need more drugs to treat the side effects. The remaining third have few or no side effects. I’m so sorry to hear that you are having such a difficult time on Letrozole. I had planned to take anastrozole for 5 years, as prescribed, but I had a number of the side effects that you are experiencing and also felt like I had aged in a short time. I was told that AIs reduce your chance of recurrence by 40 to 50%, but it is never 0%. I decided to stop after 3 months at age 70. The decision to continue or stop taking an AI is difficult, but no one else can make for us. I am not suggesting that you stop taking Letrozole. I just want you to know that you are not alone.
I wish you well.