Ca25-29 and CA 15-3: One marker going up and the other down?

Posted by shireen71 @shireen71, Mar 29, 2024

I was diagnosed with breast cancer ER positive her two negative. I was cancer free for four years and then I developed cancer in my liver MBC I am currently on Anastrozole and Virginio treatment initially my tumor marker CA 25–29 was 230 after my first treatment the markers went down to 48 and now the second month of treatment. My markers went up to 113 however, my CA 15 three markers was 118 before treatment and first month of treatment it went down to 98 second month treatment it went down to 60 my question is what does it mean when one marker goes goes down and the other one goes up after the second month of treatment

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@einnoc
I recently had a chest CT scan with contrast and I remember it burning when they injected the it but other than that, I don’t remember any side effects. Not sure if it was Omniqaque though.
Now, when I had my Sentinel Node Biopsy surgery, whatever they injected to find my sentinel nodes made me pee bright blue for about 3 or 4 days!!

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@colleenyoung

Hi @shireen71, I'm sorry to hear about your disappointing scan after 3 months on Verzenio and anastrozole. I moved your post to your original discussion so that members can see a bit more of your diagnosis and journey.

Have you had a chance to speak with your oncologist in the meantime to get a better understanding of the different indicators that the tumor markers vs the scan seem to be saying? What did you learn? Has your treatment plan changed?

Jump to this post

I took a PET scan going this week to see oncologist keep you posted

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