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Not eligible for Immunotherapy. Now what?

Lung Cancer | Last Active: May 22 5:00pm | Replies (58)

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@ladylennie

I had multiple small nodules in both lungs discovered by accident in late 2019. They were followed and stable for almost 4 years. In November 2023 they showed growth. I had a pet-ct that showed 2 nodules in my left upper lobe were suspicious. Then biopsy (bronchoscopy) of one showed adenocarcinoma. Pulmonologist did not recommend surgery because of lung function. I had 2nd opinion and we decided on surgery. Lul lobectomy and lll wedge. Both in lul adenocarcinoma, p 2. Left lower was atypical cells, aah. I still have 2 hopefully staple nodules in right lung.

Started pemetrexed carboplatin chemo and just had 2nd cycle. No side effects so far except fatigue. Will have 2 more cycles and then one year of Keytruda. First scans after surgery will be when chemo is complete in mid June. Obviously hoping for no change in right lung nodules.

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Replies to "I had multiple small nodules in both lungs discovered by accident in late 2019. They were..."

I'm experiencing this situation now. I also have multiple lung nodules in both lungs after being in remission from Stage 3-B treatment in 2008 for ten years, beginning in 2018 when they begun becoming malignant. Besides the radiation I experienced for the primary cancer in 2008, I've had four different nodules radiated since 2018 and my radiologist and oncologist are telling me we're running out of treatments. The radiologists who read my CT's continue to report that I have multiple other nodules in both lungs that appear to be growing in size. I also don't have biomarkers, but my oncologist at UCSF is considering Keytruda, based on a current trial (IMPRINT) at M.D. Anderson. He has warned me, however, that his patients who have undergone lung radiation are at a higher risk for pneumonitis when on the immunotherapy drug. I'm curious if anyone who has had radiation for slow-growing lung nodules have had experience with Keytruda.