How long will Lupron work before prostate cancer becomes resistant?

Similar situation. Had 4 rounds of chemo followed by Lupron then switched to ORGOVYX My PSA has been 0.02 for 5 years now. Had to adjust to a new normal due to side effects ie: increased weight, (still overweight) fatigue but discovered exercise is a great fix for fatigue. Good Luck. Keep fighting

Dont hit your panic button. Listen very carefully to your doctor. Not curable does not equal terminal. OK?
Best go back to your doctor for recommendations of treatment. If not satisfied, go to another doctor. All we can do is share our experiences. That is very limited. The doctors have much wider experience. Some have thousands over decades.
Dont mind me. I am just another layman, and getting long winded.

Sorry, didn't mean to overwhelm you!

So if you have a few pelvic lymph nodes that were tracer-avid (i.e., took up the PSMA tracer agent on the scan) but no visible mets out of the pelvic region in bones or organs, you have locally advanced staging. Technically it's Stage 4a, but is not Stage 4b which means distant mets.

I suspect what your onco meant was that some if not most consider the disease "incurable" once it escapes the prostate. Radiation to the pelvic areas showing cancer presence and areas in the pelvis that do not show disease but where it could be present at the cellular or micro-met level can be curative. But being declared "cured" means no detectable disease for a period of 10 years. That's a tough criterion to reach.

But as has been discussed here, because of these 2nd generation drugs the battlefield is being reshaped, so to speak. Dr Mark Scholz is one of the prominent oncologists who believes the disease can be cured these days as long as it is oligometastatic (less than 5 distant mets) or confined to the pelvis.

I am unsure what to make of the idea that you're incurable because radiation failed to kill all the cancer. I'd engage your onco and get him to explain things better.

Dont hit your panic button. Listen very carefully to your doctor. Not curable does not equal terminal. OK?
Best go back to your doctor for recommendations of treatment. If not satisfied, go to another doctor. All we can do is share our experiences. That is very limited. The doctors have much wider experience. Some have thousands over decades.
Dont mind me. I am just another layman, and getting long winded.

For me to hear incurable from my doc means he thinks all other options are a wast of time . I’m looking at cryoablation Brachytherapy or salvage prostectomy but what’s the point if they don’t provide a cure.

Thank you, good advice

The only thing I'll add is that a team approach at a cancer centre in Canada or a major clinic in the U.S. can bring advantages over being treated by a single oncology urologist:

1. You get the combined experience of the whole team, from students to senior oncologists

2. They will be up to date on the latest research (and are often researchers or teachers themselves).

3. They will have better and earlier access to new drugs, clinical trials, emerging treatments, and patient-access programmes.

An independent urologist, no matter how wonderful, might still be doing things the same way they did 5 or 10 years ago, and with PC treatment too much has changed too fast for that to be ideal.

Do NOT think that incurable equals terminal. Your cancer can still be controlled and suppressed for years in many cases, even if it cannot be cured. It can still be there but kept quiet for a time. My husband plus many of the other men who post here have lived with Stage 4 advanced cancer for many years, such that it is more a chronic disease. Many men realize they can live with prostate cancer and die with it, but not OF it. Please do not think further treatment is a waste of time!

I’m not sure how to respond on this. I’m using the Hulston Cancer in Springfield Mo and cancer of all types is all they. My Radiation doc worked there and he turned me over to my Hematologist/Oncologist who has full access to everything they stand for in this facility. Is this the independent Oncologist you mentioned or the team approach. This is really the best we have in this city but I’m willing to travel and have gone to Germany since I was diagnosed back in 2016. Do you think I’m missing something and should look elsewhere?