I have a local compounding pharmacy. After being at 4.0 for three days and falling asleep an hr or 2 before bed time, I made it through to bedtime the last 2 days! I have a med allergy list a mile long. This is my last attempt of having an oral pain med. With the great pain management doctor I have I do get respite somewhere in my body. It's tough having multiple areas of pain to try to be pain free at one time!

Yep, I felt too alert. That’s so interesting because that’s the opposite of what I heard! But everyone’s different.

I was prescribed it for mainly fatigue, actually. You may know this already from reading about it, but the suspected mechanism of action is that LDN temporarily blocks the receptors in the brain that detect endorphins. The body then produces additional endorphins, which can improve fatigue and pain relief.

The first dose, I felt hyper-alert, ran a whole bunch of errands when I normally would have been tired, then couldn’t sleep. It got better the next day, but still I felt wired. I ultimately had to start at a lower dose. I can’t say I’ve noticed much difference in my pain or GI symptoms, just a slight improvement in my fatigue.

Compounding pharmacies can make any formulation usually: liquid, topical cream, capsule, or tablet. My dad used to take a liquid, but it was very expensive and had to be shipped refrigerated, so we switched.

There were two local, independent compounding pharmacies I checked out, which also both deliver. The pharmacy I now use is CareFirst Specialty Pharmacy in New Jersey (there’s a different one with the same name somewhere). I don’t live in NJ, but they ship all over and seem to do a lot of mail order business. They specifically can make any size tablet from .5 mg and up.

I might have said this already somewhere, but my doctor said it has the best price she’s come across. I take 6 mg, and I think I pay about $78 for a 90 day supply.