I have improved greatly on 10 mg of Camzyos. I am labeled "severe" HCOM. My doctor wrote ,"impressive results" on my chart regarding Camzyos. I did not feel well when I first started the drug. A nurse practitioner adjusted my metoprolol which made the difference for me. I mention this in hopes that someone else will consider this if they are not feeling well initially on Camzyos. A few days ago, I began taking 15 mg to see if I can improve even more.