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Orgovyx extreme fatigue side effects

Posted by mikejf @mikejf, Apr 22 9:51am

I have been using Orgovyx several years for prostate cancer and am now have in extreme fatigue side effects during the afternoon. I take Orgovyx late morning every day and side effects kick in around 3p.m. I was wondering if I switched to taking Orgovyx at night in stead if side effects during day would be reduced

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hector13 | @hector13 | Apr 25 9:23am
In reply to @jane55 "Hi, Can you please send the article? I tried to find it on the Prostate Cancer..." + (show)
@jane55

Hi,
Can you please send the article? I tried to find it on the Prostate Cancer Foundation website without any luck.
Thanks,
Theresa

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Reply for Theresa. I receive hard copies from the Prostate Cancer Foundation, so I can't cut and paste it to this site. I suggest you contact them at 1-800-757-2873 to get on the mailing list. I expect they could send you the April 2024 Newsletter if you request it. There is often good information in them. Thanks for the inquiry!

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jane55 | @jane55 | Apr 25 2:54pm

Thanks for the quick response.
Theresa

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leeaniel | @leeaniel | Apr 25 10:44pm

I take my Abilaterone at 2am, then take a nap after my first meal around 8:30am. My solution for feeling tired.

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leeaniel | @leeaniel | Apr 25 10:51pm
In reply to @hector13 "I have been taking Orgovyx for a while now. When I received the first month supply..." + (show)
@hector13

I have been taking Orgovyx for a while now. When I received the first month supply from the urology pharmacist, he warned me that I would definitely be experiencing major fatigue from the drug. That hasn't happened. I have not been tired, but I do get the hot flushes on occasion. Everyone's physiology is different, but I believe exercise is the main reason I have avoided fatigue. We cannot control much while we deal with prostate cancer, but we can choose to exercise. I play singles tennis twice a week for an hour. I am 69 years old, but I am determined to keep up this routine. I live in South Texas, which means in the summer I have to play in 105 degree heat, but I have done it most of my life so I plan to keep at it.
The Prostate Cancer Foundation recently mailed out their April 2024 newsletter with an important article entitled: "Hormone Therapy: Be FIERCE with Exercise". It states, "The effects of exercise have been vastly understudied in men with metastatic prostate cancer". The studies are not over, but the article also states, "What we do know is that you can fight ADT's negative effects on your body".
The message is clear. Any form of exercise will help us fight prostate cancer and have a better quality of life. The FIERCE program is a good candidate for a future Mayo Clinic seminar for the Prostate Cancer Support Group.

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I have PC stage 4 and sarcopenia. High intensity barbell exercises for about 15 minutes every other day. Makes me feel good 😊. Good luck.

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leeaniel | @leeaniel | Apr 25 11:00pm

I forgot to mention that I take about 90gr of protein daily, I'm 86 150 lbs.

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1 reply
Moderator
Colleen Young, Connect Director | @colleenyoung | Apr 29 11:49am

Here are a few related discussions:
- Hot flashes, fatigue 4 months after radiation and Orgovyx
https://connect.mayoclinic.org/discussion/hot-flashes-fatigue-4-months-after-radiation-and-orgovyx/

- Zytiga and Orgovyx: What helps side effects, fatigue and disinterest?
https://connect.mayoclinic.org/discussion/zytiga-and-orgovyx/

- What's your experience with Orgovyx (relugolix)?
https://connect.mayoclinic.org/discussion/the-orgovyx-thread/

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ava11 | @ava11 | Apr 29 8:15pm
In reply to @leeaniel "I forgot to mention that I take about 90gr of protein daily, I'm 86 150 lbs." + (show)
@leeaniel

I forgot to mention that I take about 90gr of protein daily, I'm 86 150 lbs.

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leeaniel,
How much of your protein from food and powders, if any? I am trying to get my protein from vegetarian sources like soy, nuts, beans, legumes and vegetables.
I am on Orgovix for 29 days and I already feel fatigue!

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1 reply
leeaniel | @leeaniel | May 13 3:28pm
In reply to @ava11 "leeaniel, How much of your protein from food and powders, if any? I am trying to..." + (show)
@ava11

leeaniel,
How much of your protein from food and powders, if any? I am trying to get my protein from vegetarian sources like soy, nuts, beans, legumes and vegetables.
I am on Orgovix for 29 days and I already feel fatigue!

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All the ones you mentioned. I'm addicted to steamed green onions, mushrooms, beans and whatever other veggies are available at the market. I'm fond of almonds and seeds that I blend and sprinkle on my salads and follow Dr Fuhrman's (YouTube) recommendations but I always add a bit of meat for flavor and extra proteins. Last but not least 15 minutes of barbell and two 5 minute chair exercises to control my sarcopenia

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1 reply
leeaniel | @leeaniel | May 13 3:48pm
In reply to @leeaniel "All the ones you mentioned. I'm addicted to steamed green onions, mushrooms, beans and whatever other..." + (show)
@leeaniel

All the ones you mentioned. I'm addicted to steamed green onions, mushrooms, beans and whatever other veggies are available at the market. I'm fond of almonds and seeds that I blend and sprinkle on my salads and follow Dr Fuhrman's (YouTube) recommendations but I always add a bit of meat for flavor and extra proteins. Last but not least 15 minutes of barbell and two 5 minute chair exercises to control my sarcopenia

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BTW I exercice every other day or sometimes 3 x a week. One day of rest is
important between exercise. Search YouTube for a video that's suitable to
you.

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1 reply
mikejf | @mikejf | May 13 4:33pm
In reply to @leeaniel "BTW I exercice every other day or sometimes 3 x a week. One day of rest..." + (show)
@leeaniel

BTW I exercice every other day or sometimes 3 x a week. One day of rest is
important between exercise. Search YouTube for a video that's suitable to
you.

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I workout 5 days a week but alternate between 35 minutes weight lifting and 30 minutes cardio (elliptical/treadmill) so one day weights next day cardio next day rest then repeat this pattern
Works for me.

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