What is desired level of Vitamin D for those with osteoporosis?

Posted by ripley @ripley, Apr 26 3:42pm

I'm trying to find out what the desired blood levels of Vitamin D should be if you have osteoporosis, My levels have always been on the low side of the range 30-100. Six months ago it was 27.8 so my Dr increased my Vitamin D supplement to 3,000 IU/day. Now my levels are 40.9. I read they should be above 50. Can anyone provide more information?

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windyshores | @windyshores | Apr 26 5:19pm

On Tymlos I did 3,000 units/day because I read that Tymlos "eats" D3. My level was 52 before starting Tymlos at a dose of 2,000 units/day and stayed stable in the low 50's throughout treatment. Now I am back down to 2000.

rosemariegd | @rosemariegd | Apr 27 8:22am

I take 5000 IUs a day and my D3 level is 51.

gently | @gently | Apr 27 10:23am

nmol/L would be a higher number than ng/ml to convert multiply ng/ml by 2.5
The endocrinologist I consult with likes 40 to 70 ng/ml.
So 100 to 175 nmol/L

babs10 | @babs10 | Apr 27 3:54pm

@ripley

The Vitamin D Counsel (who knew?) standards:

Deficient: 0-40 ng/ml (0-100 nmol/l)
Sufficient: 40-80 ng/ml (100-200 nmol/l)
High Normal: 80-100 ng/ml (200-250 nmol/l)
Undesirable: > 100 ng/ml (> 250 nmol/l)

bobweller | @bobweller | Apr 27 5:36pm

Get the blood test and compare to the normal range for calcium. Look it up in Google too.

gently | @gently | Apr 27 8:10pm

In reply to @bobweller "Get the blood test and compare to the normal range for calcium. Look it up in..." + (show)

bobweller, medical practitioners like to see a higher level of D with osteoporosis and cancer. https://neurosciencenews.com/vitamin-d-microbiome-cancer-25990/
Some osteoporosis medications employ D so effectively that they lower serum levels notably Tymlos and Forteo.

karenidfly | @karenidfly | Apr 28 9:29am

I think it depends on the results of blood test. Even tho I was getting 2000/day, my test came back too low so I was upped to 5,000/day. Doc also suggested changing to a liquid vitamin D b/c I was on the low end of acceptable D amounts.

babs10 | @babs10 | Apr 28 9:45am

@ripley, Are you asking how much Vitamin D a person should take per day or what the actual recommended levels of vitamin D would be on a blood test? Or both? Thanks.

ripley | @ripley | Apr 28 11:42am

In reply to @babs10 "@ripley, Are you asking how much Vitamin D a person should take per day or what..." + (show)

I know the normal range for Vit D is 30-100, but I'd like to know what number within that range is best for those with osteoporosis.

Michael Lavacot | @michaellavacot | Apr 28 1:35pm

From the research I have done, the optimum 25(OH) vitamin D level for osteoporosis is 30-50ng/mL (75-125nmol/L). You want to adjust your vitamin D3 intake to get into that range which is typically around 1000 to 2000 IU/day.

Here are the footnotes for the studies if you want to look them up.
1 - https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional
2 - https://pubmed.ncbi.nlm.nih.gov/28722941/
3 - https://link.springer.com/article/10.1007/s00198-023-06802-x
4 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471662/
5 - STOP IT Trial https://academic.oup.com/jcem/article/107/5/e1932/6504006