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Low Dose Naltrexone and Neuropathy

Posted by lorirenee1 @lorirenee1, Jan 6, 2020

Hi everyone. Lori Renee here. I have been on Low Dose Naltrexone for about 2 weeks. It may be too soon to post about this medication, but I thought I would post now, and post again, in about 2-4 weeks. Bottom line is that Low Dose Naltrexone has helped considerably with my foot neuropathy. My pain is sometime gone, and usually only reaches a level 5 or so, sometimes. Usually, it is about a 2-3, kind on a low level foot throbbing. Enough to be annoying, but not enough to want to cut my feet off. Without it, I wanted to cut my feet off. Certain problems do remain, so my feet are far from normal still. I put on shoes, and feel like my socks are bunched up, or that there are pebbles in them. It takes me a long time to find a shoe to wear. The balls of my feet still feet like they have been stuck in cement, but not all the time. My toes still feel stuck together, or too widely spread. All crazy sensations of neuropathy. So Low Dose Naltrexone has not taken all the crazies away. However, the pain is so much lower, that I am amazed. I have only used Kratom once in two weeks, which is remarkable. I have no side effects at all from the drug. It is not covered by my Medicare insurance, but is about 35 bucks a month. Not too bad. Anyway, it really is the best pain killer I have tried, other than Kratom. I don't have to taste the vile Kratom, so that is very good. I suggest that everyone give it a try. I read that it helps approximately 25% to 40% of people that try it. The endorphin rush it produces is loaded with pain fighters. Yes, give it a try. I will post again about it, as I use it more. Love to all, Lori Renee

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bettyg81pain | @bettyg81pain | Apr 27 2:28pm

Do you need a Rx from a doctor for LDN?

REPLY
emo | @emo | Apr 28 9:58am
In reply to @daj3333 "Do you mind if I ask where is a Publix compounding pharmacy? I didn’t know the..." + (show)
@daj3333

Do you mind if I ask where is a Publix compounding pharmacy? I didn’t know the did compounding. I pay $54 for a 30 day supply of LDN.

Jump to this post

I know this doesn’t answer your question, and can’t remember off the top of my head (threw out the receipt), but I’m pretty sure I pay around $78 for a 90-day supply from Care First Specialty Pharmacy in New Jersey. I take 6 mg tablets (tablets are cheaper than capsules). I don’t live in NJ; I live in Illinois and my doctor prescribes it frequently and has found they have the best rate of what she’s come across
so far. If you call them, they’ll price it out for you.

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bayhorse | @bayhorse | Apr 28 1:08pm

Hi, Lori Renee: Could you please tell me what dose of LDN you started with? I have 4.5 mg capsules, and they're knocking me out. My doctor was just guessing when he prescribed, as didn't have much experience with the drug.
Thanks for any help you can give.

REPLY
1 reply
emo | @emo | Apr 28 1:24pm
In reply to @bayhorse "Hi, Lori Renee: Could you please tell me what dose of LDN you started with? I..." + (show)
@bayhorse

Hi, Lori Renee: Could you please tell me what dose of LDN you started with? I have 4.5 mg capsules, and they're knocking me out. My doctor was just guessing when he prescribed, as didn't have much experience with the drug.
Thanks for any help you can give.

Jump to this post

4.5 mg is the most common dose that’s documented in the limited research, but some people do better with a higher or lower dose.

Did you start off right off the bat on 4.5 mg? I’ve never heard of that before.

It’s most common to start with a low dose (usually 1 mg, or even .5 mg) and then slowly increase the dose over time. For example, I’m very sensitive to medications and we first started at .5 mg, but I was too wired and had trouble sleeping, so I had to go down to .25 mg to begin.

If you’re having trouble adjusting to 4.5 mg, it could be that it’s too high a dose for you and you may want to consider if not lowering the dose that starting at the bottom and slowly titrating

But if you’re using capsules instead of tablets, the drawback is that you can’t cut those, unless you want to dilute them into a solution, but that gets complicated. I’ve also looked into three different specialty pharmacies and capsules are more expensive than tablets.

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1 reply
barbbielor | @barbbielor | Apr 28 1:47pm
In reply to @bayhorse "Hi, Lori Renee: Could you please tell me what dose of LDN you started with? I..." + (show)
@bayhorse

Hi, Lori Renee: Could you please tell me what dose of LDN you started with? I have 4.5 mg capsules, and they're knocking me out. My doctor was just guessing when he prescribed, as didn't have much experience with the drug.
Thanks for any help you can give.

Jump to this post

I was started at 1 mg. Had problems. Waited a week and started at 0.5. That was the end of Dec. Have had problems every time I up it. Now staying at one dose for a month before going on. Just started 4.0 this week.

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1 reply
emo | @emo | Apr 29 2:48am
In reply to @barbbielor "I was started at 1 mg. Had problems. Waited a week and started at 0.5. That..." + (show)
@barbbielor

I was started at 1 mg. Had problems. Waited a week and started at 0.5. That was the end of Dec. Have had problems every time I up it. Now staying at one dose for a month before going on. Just started 4.0 this week.

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I had similar issues, but instead of staying on the same dose longer, I increased by just a quarter mg at a time, every two weeks, and that seemed to work for me. I hope it helps you and the rest of the titration goes more smoothly.

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bayhorse | @bayhorse | Apr 30 7:30pm
In reply to @emo "4.5 mg is the most common dose that’s documented in the limited research, but some people..." + (show)
@emo

4.5 mg is the most common dose that’s documented in the limited research, but some people do better with a higher or lower dose.

Did you start off right off the bat on 4.5 mg? I’ve never heard of that before.

It’s most common to start with a low dose (usually 1 mg, or even .5 mg) and then slowly increase the dose over time. For example, I’m very sensitive to medications and we first started at .5 mg, but I was too wired and had trouble sleeping, so I had to go down to .25 mg to begin.

If you’re having trouble adjusting to 4.5 mg, it could be that it’s too high a dose for you and you may want to consider if not lowering the dose that starting at the bottom and slowly titrating

But if you’re using capsules instead of tablets, the drawback is that you can’t cut those, unless you want to dilute them into a solution, but that gets complicated. I’ve also looked into three different specialty pharmacies and capsules are more expensive than tablets.

Jump to this post

Gee, you were wired on the LDN? I keep hearing it can make people sleepy. How interesting... Also interesting that it comes in tablets. The compounding pharmacy that's most popular where I live only makes capsules. Are the specialty pharmacies you looked at local or are they online? Thanks again for any info you can give...

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1 reply
bayhorse | @bayhorse | Apr 30 7:32pm
In reply to @barbbielor "I was started at 1 mg. Had problems. Waited a week and started at 0.5. That..." + (show)
@barbbielor

I was started at 1 mg. Had problems. Waited a week and started at 0.5. That was the end of Dec. Have had problems every time I up it. Now staying at one dose for a month before going on. Just started 4.0 this week.

Jump to this post

Hi barbbielor: Wondering what kind of problems you experienced when you upped dosage?

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