I’ve had SLL (same as CLL but predominantly in the lymph system vs. blood) for many years and declined to the point that my oncologist recommended treatment. I started oral Venetoclax (Venclexta), a BCL2 inhibitor, plus infusions of Obinutuzumab (Gazyva), a CD20 inhibitor, immunotherapy and targeted therapy two months ago and my bloodwork and all my symptoms dramatically improved within the first two weeks.

Treatment symptoms are mild compared to chemo and you may wish to ask your oncologist about this treatment. While there is no cure for CLL/SLL, my oncologist says he consistently finds longer and deeper remissions, along with lower levels of residual disease with this protocol than with all other treatments including BTK inhibitors.