What comes after Evenity?

Posted by laurensb @laurensb, Dec 1, 2023

I have been been on Fosamax for 6 years total starting in 2009 with various drug holidays during the years. I was on Raloxifene for 3 years. Started Evenity in June. What are people taking after the year of Evenity is up?

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susanfalcon52 | @susanfalcon52 | Apr 23 7:08am

In reply to @windyshores "My doc says to wait 2-3 months after Evenity to do Reclast. (After Tymlos, it is..." + (show)

windyshores,
What does Dr. McCormick say about this? Meaning, the wait time between Evenity and Reclast.

susanjane77 | @susanjane77 | Apr 23 10:15am

In reply to @susanfalcon52 "windyshores, When do you have your Reclast infusion? Mine is scheduled for June. Anxious, of course...." + (show)

Doctors never agree which is so frustrating! I trust my endocrinologist more as I am also hypothyroid. I have been taking Reclast infusions for a few years now with NO side effects. I am curious if my doctor is going to change to another drug this year as I heard you cannot take the same for so many years. Good luck !

kristie2 | @kristie2 | Apr 24 9:19am

In reply to @susanfalcon52 "windyshores, What does Dr. McCormick say about this? Meaning, the wait time between Evenity and Reclast." + (show)

We all face this coming off of Evenity . Would like to know if coming off of Evenity is more than a month before starting Reclast .My endo said a month . Would like to know what McCormick has to say .

windyshores | @windyshores | Apr 24 5:14pm

In reply to @kristie2 "We all face this coming off of Evenity . Would like to know if coming off..." + (show)

McCormick advises using CTX for transitions. My own doc, who is very good, says Evenity takes time to mineralize so no rush, maybe 2-3 months or even 4 from last injections.

wkay1212 | @wkay1212 | Apr 24 7:07pm

In reply to @gravity3 "I'll be getting my fourth injections this month. My endocrinologist wants me to begin prolia after..." + (show)

What is your biggest concern about Prolia? I just finished my Evenity Injections and the plan for me is Prolia. I also have an issue with a stress fracture that is not healing.

drsuefowler | @drsuefowler | Apr 25 9:08am

In reply to @wkay1212 "What is your biggest concern about Prolia? I just finished my Evenity Injections and the plan..." + (show)

@wkay1212, I also have a stress fracture that is not healint, but I am taking Tymlos. Your experience is more evidence for me that the anabolics just help trabecular bones, especially the spine. Especially at first, I think they make cortical bones porous. I considered stopping the Tymlos to make my bone heal, but am afraid to do that without an absorptive medication.

My endo wants me to take Prolia after Tymlos, but I told him I don't want to. I am afraid of taking a medication that has side effects that could last a long time, and I don't want to take Prolia for the rest of my life.

windyshores | @windyshores | Apr 25 9:17am

In reply to @drsuefowler "@wkay1212, I also have a stress fracture that is not healint, but I am taking Tymlos...." + (show)

@drsuefowler I was told Tymlos helps healing for fractures.

I had a 9% gain in hip which is partly trabecular and partly cortical. I was told that Forteo results in increased porosity more than Tymlos. (Another poster had some interesting ideas on whether porosity means flexibility.)

cat1203 | @cat1203 | Apr 25 9:39am

In reply to @wkay1212 "What is your biggest concern about Prolia? I just finished my Evenity Injections and the plan..." + (show)

Prolia causes a rebound effect when you stop it. Your bones go back to worse than baseline and fracture risk is increased. So you must stay on it forever (which, depending on your age, might be a reasonable course of action as long as you're not having any side effects that you can't live with) or take a bisphosphonate after going off Prolia. Whatever bone drug you take, whether antiresorptive or anabolic, is going to have side effects which you personally may or may not experience. If you decide to do Prolia, know what the side effects are and if the benefits for you outweigh the risks to you. Different people will answer that question differently. The main problem with Prolia is the rebound effect which is unique to that drug. If you find you can't tolerate it for some reason, you can't just stop it. You must take a relay bisphosphonate. Those have their own side effects to consider. You'll also have to consider what your insurance will cover. It's worth a discussion with your doctor for what the exit plan is for coming off Prolia.

sando | @sando | Jun 22 4:19pm

In reply to @windyshores "I am doing a 20% test dose of Reclast when I finish Evenity (after Tymlos). McCormick..." + (show)

Hi @windyshores
Please let me know if after Evenity, then TYMLOS, you will try 20% of Reclast. ( I may have got this order of meds wrong but I’m struggling too and trying to figure out what to do , after evenity..they only say Reclast or Prolia. I ask the e we endo if I could try 20% but she said no, we’re not set up for that. How do you find a Doc like yours. Was there paperwork, redone involved? I have to do oral surgery on top of everything so want to do it asap before I start anything by the end of July! In a crunch here..help

sando | @sando | Jun 22 4:31pm

In reply to @windyshores "@mayblin what an interesting idea! The liquid version of Fosamax... I have been told that Reclast..." + (show)

@mayblin
Hi, who is Keith McCormack? Is he published anywhere? It sounds like you will explore liquid Fosamax, not Prolia & Reclast…I’m very interested in any alternatives too…. I get consults from 2 Endocrinologists but they both lean only to the 2 common follow ups. I asked what if you’re allergic as it lasts a year…she mentioned some minor ones ..take typical etc.are there rational docs we can get that will be open?. How do we get them..no one seems to want to try anything else.any advice with how you did it would be most welcome!.