Orgovyx extreme fatigue side effects

I don't take that particular med but I do get fatigued from my present meds. Seems it's always a battle with the fatigue. I try to keep moving even when I don't want to. My work day ends early afternoon and then it's my coffee and relaxing in the chair. I wish you the best on your journey.
Just wanted to add, the paperwork I received to fight fatigue listed mowing the lawn, I thought my wife made that up.

Thanks for comment. Yes I exercise regularly elliptical and weight lifting. And it does help but after an hour or so i get totally leveled with extreme fatigue. I think it might be because testosterone is totally depleted as result of ORGOVYX kicking in during day

I have been taking Orgovyx for a while now. When I received the first month supply from the urology pharmacist, he warned me that I would definitely be experiencing major fatigue from the drug. That hasn't happened. I have not been tired, but I do get the hot flushes on occasion. Everyone's physiology is different, but I believe exercise is the main reason I have avoided fatigue. We cannot control much while we deal with prostate cancer, but we can choose to exercise. I play singles tennis twice a week for an hour. I am 69 years old, but I am determined to keep up this routine. I live in South Texas, which means in the summer I have to play in 105 degree heat, but I have done it most of my life so I plan to keep at it.
The Prostate Cancer Foundation recently mailed out their April 2024 newsletter with an important article entitled: "Hormone Therapy: Be FIERCE with Exercise". It states, "The effects of exercise have been vastly understudied in men with metastatic prostate cancer". The studies are not over, but the article also states, "What we do know is that you can fight ADT's negative effects on your body".
The message is clear. Any form of exercise will help us fight prostate cancer and have a better quality of life. The FIERCE program is a good candidate for a future Mayo Clinic seminar for the Prostate Cancer Support Group.

I started taking Orgovyx in the morning at first and did experience some fatigue in the afternoon. I switched to taking it in the evening and had no fatigue after that...in fact, I had little fatigue in general from my 18 month treatment cycle. I have now been off Orgovyx for 3 weeks and am having only very minor hot flashes and experiencing increased libido. I feel that Orgovyx is a much better choice than Lupron as the side effects leave more quickly after stopping.

Thanks for your reply and support. I agree with you about exercise but my experience is different. I have advanced prostate cancer and have been using ORGOVYX for about 3 years now. I do feel better psychologically as well as physically from exercise. I also have gained a great deal of weight as a result of meds and not very good diet of course. Still having the fatigue but slightly better when i exercise (about 5 days a week)Thanks again

I just finished 12 months of Orgovyx, came off it on 4 April.

I took mine each night around 11 pm.

Fatigue, yes, mornings were ok, late afternoons and evenings, very noticeable.

I exercised pretty much every day, either at the gym riding the indoor bike, lifting weights, swimming, outside, riding my bike, playing pickleball, active vacations such as skiing and hiking in Colorado, gardening chores, walking our dog (A yorkie who loves to sniff so average pace was 35 minutes a mile, was it really "exercise!?")....

My wife will tell you, there were times where I just took the damn nap!

Interestingly, been off it three weeks, fatigue and muscle and joint stiffness more or less gone, the hot flashes, the inverse, more and more severe, ugh. It will be interesting to see what my T is at the three month labs and consultation, started at 600+.

Like others, a study of one...

Kevin

Seems that residual effects are common to all adt. Maybe this explains differing time to recurrence. Some residual blood levels prevent recurrence for a period post therapy

My current plan involves intermittent adt in hopes of getting more accurate scans with slight psa rise so we can more precisely target hot spots. Might take a while if residual effects described here play out on me.

I’d be reluctant to take Orgovyx at night being concerned that any SEs could be pronounced because of fewer distractions. I’ve been on it for two months now. SEs are no libido (I mean it is gone), occasional dizziness, heart racing, sleeplessness, and fatigue. But nothing overwhelming. Just starting my third month. PSA has dropped from 16.5 to 1.45 in 60 days. Awaiting my RT to start in August after Barrigel procedure. Intend to start a 12 month holiday next January.

Hi,
Can you please send the article? I tried to find it on the Prostate Cancer Foundation website without any luck.
Thanks,
Theresa