I had atypical ductal hyperplasia so my doc put me on 10mg of Tamoxifen every other day. Joint pain, acne, weight gain started pretty quickly. Additionally my liver became "fatty". I was going to keep taking it hoping symptoms would calm down but had to go off of it for a surgery. I was on Tamoxifen for 6 months. A few months after my surgery I had a pelvic MRI. My left ovary was enlarged and I had a spot on my uterus. That ended up being a spot on a polyp on my uterus and luckily the enlarged ovary was a result of that polyp and not ovarian cancer. The spot was hyperplasia but nothing had turned into full blown cancer yet. I had a hysterectomy. These issues are possible side effects of Tamoxifen. My breast oncologist wants me to go back on Tamoxifen stating she thinks this was all a coincidence but I'm not convinced and not sure what to do.