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What is Your Experience with Anxiety?

Depression & Anxiety | Last Active: May 7 8:09am | Replies (80)
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@ellemccope

Zoloft had helped me for 24 years with anxiety (panic disorder and generalized anxiety disorder and depression) and then around the peak of the COVID pandemic, it stopped working. 😔 I had apparently built a tolerance to it. Since then, my psychiatrist and I have tried numerous SSRIs, SNRIs, and even a couple of anti-psychotics, but I either couldn’t tolerate the side effects or they did absolutely nothing. The only med that is partially working is Mirtazapine (a tetracyclic) and that’s only giving me a partial response. Now, my psychiatrist wants to add Lamictal, but I am afraid due to side effects. Lamictal is FDA approved for treatment of epilepsy and Bipolar 2. I have neither. I just have major depressive disorder and anxiety. Has anyone had any luck with Lamictal who just has regular depression (not bipolar) and anxiety?

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Replies to "Zoloft had helped me for 24 years with anxiety (panic disorder and generalized anxiety disorder and..."
silverpaw | @silverpaw | Apr 22 1:10pm

Yes I'm on Lamictal and It is working Great!

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sksnow | @sksnow | Apr 30 8:10am

Wow, I literally could have written this myself. Ive been on Zoloft for 22 years, it stopped working for me too.
I am currently undergoing chemo,( just finished my last round)for small cell lung cancer which has caused me a condition called SIADH. The waiting for scans to see if im going to make it or not is brutal to put it mildly.
SSRIs and SNRIs are a no go because they will make my sodium drop even lower. I was recently prescribed Lamactil, for treatment resistant depression (have tried SEVERAL meds over the years) and because it doesn’t cause sodium issues. My depression and anxiety is off the charts but I am so petrified of putting an unknown substance ,Lamactil, in my body that i cant bring myself to physically remove it from the bottle and put it in my mouth. It’s ridiculous. I NEED help but am too scared. Anyone have advice that might help me take that plunge?

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