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M-Spike, High Kappa and Kappa/Lambda Ratio

Blood Cancers & Disorders | Last Active: May 7 11:35am | Replies (78)
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@leslie2121

I think your assessment of where you are is right. I’ve heard a FLC above 100 is where they get concerned.
Have you tried curcumin? Many good results found from the somewhat limited studies on stopping or slowing progression.
My FLCs dropped ~25% after starting 3-4 gms/day. I’m probably repeating myself here.

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Replies to "I think your assessment of where you are is right. I’ve heard a FLC above 100..."
Kappa King | @kappaking | Apr 20 4:58pm

I would try curcumin, however I'm concerned about how I would tolerate it given my comorbidities of esophagitis and urinary tract issues (neither related to MM).

I'm a little confused about the free light chain reading. The absolute number of IgA is above 2200, and the absolute number of free kappa light chains is above 300. Understanding that you're likely not a physician, do you (or anyone else) know if one has a high free light chain reading (with associated high FLC ratio) AND a high heavy chain reading, does it mean a likely case of light chain myeloma? I had been of the understanding that the conditions for light chain myeloma is when NO heavy chains are made and ONLY light chains exist in excess.

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