I am very interested in this discussion of how long the effects of Lupron stay after the Lupron shots stop. I had my last shot 3 months ago. I remember reading about all the side effects of Lupron and loss of muscle mass was the one I feared most. Even though I was 83 when diagnosed I was very physically active, taking care of a large yard by myself, repairing decks, hauling everything from a hundred bags of mulch to 60 lb bags of sand and paver base. I also went to the gym 3 days a week for 2 to 3 hours lifting weights.

My mineset after the diagnosis was that I would continue, as usually, everything I did before the the prostate cancer. Even during radiation, I'd get off the table and go to the gym. I'd arrive feeling tired but feel almost normal when I left. My ability to lift the same amout of weight has not dimished. It may be that I could have increased the weight w/o the lupron but at least my strength and muscle mass does not seem to have changed.

I take additional vitamins to helf prevent bone loss and I have a small very quiet fan I found on Amazon that keeps me cool at night for the hot flashes.

I am a firm believer that my getting angry sometimes, and forcing myself to overcome the bad hand that was dealt, is the primary reason I do not suffer as much from the side affects of Lupron as some on this site have.

Believe me. I have had to deal with other side effects from the intense radiation to kill the cancer which had spread to my lymphnodes. The mild lymphedema, the rectal bleeding.

But my mineset has made my life with advanced prostate cancer better than I could have hoped for. And there is another benefit, after a hard days work.........happiness that you did it and that you feel as good as you do. I reward myself with something I enjoy just about every afternoon/evening. The company of my wonderful, lovely wife, a stiff drink and a cigar, while lisening to our favorite music.