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PET scan vs Cerebrospinal fluid (CSF) test

Brain & Nervous System | Last Active: May 14 3:19pm | Replies (16)

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@jenatsky

The is from NIH “ Amyloid PET and CSF biomarkers can identify early AD with high accuracy. There were no differences between the best CSF and PET measures and no improvement when combining them. Regional PET measures were not better than assessing the global Aβ deposition.” I would guess that the PET is more costly hence pushback from Medicare contractors.

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Replies to "The is from NIH “ Amyloid PET and CSF biomarkers can identify early AD with high..."

Well of course cost is the reason. But its not clear to me they can disallow a PET

FDA-approved approved Leqembi® is the latest medication for Alzheimer’s treatment. That means Medicare Part B now covers the pricey drug.

However, Part B enrollees are still responsible for 20% of Leqembi’s cost, currently listed by its manufacturer at $26,500 annually.

Patients with early-stage Alzheimer’s qualify for Leqembi, and Medicare coverage depends on being enrolled in a registry, among other rules.

Centers for Medicare & Medicaid Services | CMS (.gov)
https://www.cms.gov › view › ncd
NCD - PET (FDG) for Dementia and Neurodegenerative Diseases (220.6.13)
An FDG-PET scan is considered reasonable and necessary in patients with a recent diagnosis of dementia and documented cognitive decline of at least 6 months, ...