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Bone turnover markers (CTX and P1NP): do you have a baseline?
Osteoporosis & Bone Health | Last Active: Sep 20 11:58am | Replies (240)Comment receiving replies
Hi mayblin, I believe I have high baseline CTX from my hypercalciuria. I'm was peeing out more calcium than I could absorb in a day. While I have lowered urine calcium, it's still way to high at about 350mg/day. I'm still trying to track down the cause. Hopefully this year I will be able to figure it out.
I did not have good outcomes on Evenity. I gained only about 2%. I believe that the results are again related to my high urine calcium. You can't build bone if your net daily calcium is near or below zero.
Prolia seemed like the right choice if not the only choice after Evenity for me. Fingers crossed I can tilt the calcium balance in my favor and see some improvements. I'm taking in about 1500mg or more calcium per day.
Thanks for asking. I have appointment this year with the best nephologist and endocrinologist I could find. They should be able to help me more.
Mike
Replies to "Hi mayblin, I believe I have high baseline CTX from my hypercalciuria. I'm was peeing out..."
Hi @michaellavacot could you elaborate your choice of prolia over a bisphosphonate after evenity in your particular case? Thank you!
Mike,
I was on Evenity for one year T score in spine -4.6 . Then after one year T score -3.3. Then I was put on Prolia and after one year T score 3.2. My endocrinologist now suggest Reclast basically no change. Can you please give me your insight on switching at this time to reclast ?
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Hi @michaellavacot i am sorry to hear that evenity didn’t help building any significant bones for you. It seems your hypercalciuria, whatever the etiology might be, is robbing calcium from your bones, and your baseline CTX reflected that.
Hope you and your team of physicians will figure out the cause of hypercalciuria, whether it’s endocrinal origin, or renal origin or due to some other rarer disease state. Even if it turns out to be idiopathic, a proper control and treatment of hypercalciuria becomes a priority.
Best wishes!