I am 69 and have been using estradiol for 10 years or more for vaginal atrophy symptoms. I also use an OTC called vulva care. I am a breast cancer survivor; I was a little worried after reading comments. I found this last night https://www.breastcancer.org/research-news/vaginal-estrogen-safe-for-women-with-breast-cancer so for me it means it should be safe because, in regards to uterine or ovarian cancer, I have had a total hysterectomy. Like people said, everyone is different. I am going to start using the coconut oil in between estradiol, though, since I already use it for my diet.......much cheaper than the vulva care! Thanks 🙂