Yes, no weekend doses, just 10 mg every M, W, and F and I have had no side effects. I just want to clarify I have not been diagnosed with breast cancer, but with a pre- malignant marker (Atypical Ductal Hyperplasia). This regimen was prescribed by my doctor at the high risk breast clinic at Mayo Rochester after my wide excision biopsy (lumpectomy) confirmed ADH but no cancer. The ADH plus dense breast tissue and no children puts me in the high risk category. She said research has shown this Baby Tam dose” as they call it, can cut my 30% + lifetime risk in half. I read the research, was impressed with the results and that the side effects at this low dose level were comparable to the placebo. So I decided to take it. I have been pleased so far.