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Anyone with MGUS, do you have joint pain?
Blood Cancers & Disorders | Last Active: Mar 29 10:24am | Replies (44)Comment receiving replies
I have MGUS and fatty liver disease and obesity and I have pain all the time. Doctor says it's not from MGUS but deep down I feel it is. But my levels are high all the time and dr says that there okay but it scares me alot because 1 cancer runs in my family. I have alot of back problems my posture is bad my lower back hurts all the time and shoulders close to my neck hurt alot and it burns. And I was told by a different dr that I have Fibromyalgia but I don't know or think it's that I think and feel like it's MGUS . IM SENDING PRAYERS FOR EVERYONE AND HOPE EVERYONE GETS TO FEELING BETTER
Replies to "I have MGUS and fatty liver disease and obesity and I have pain all the time...."
Hi Sheryl. My hematologist also says MGUS doesn’t cause pain, so I think it’s likely the pain is from something else. The insulin resistance theory is interesting because being overweight and having a fatty liver are both associated with insulin resistance/diabetes. I would make sure you are being monitored for that with HbA1c levels in serum periodically. There is also a higher incidence of MGUS in patients with autoimmune diseases which certainly can cause joint pain. Many women with autoimmune diseases are told they have fibromyalgia, sometimes even without being tested for autoimmune disease. I would ask to be tested for AI disease and see a rheumatologist for that if anything shows up that’s abnormal. I have MGUS, lupus and rheumatoid arthritis. The last 2 cause significant joint pain. In the meantime if you’re able to take naproxen or ibuprofen, either might give you some relief but that’s only treating the symptoms not the cause. I do hope your Dr will look into the AI disease and insulin resistance possibilities and you get some answers and relief. Weight loss would help the joints, liver, insulin resistance and make you healthier in general. I know it’s easier said than done but very important to do. Good luck. Sending healing thoughts your way!
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Hi Sheryl
Some recent research has shown that insulin resistance seems to be the cause of (Fibro) pain. This explains a lot for me. I have MGUS, fatty liver, and obesity, and insulin resistance with varying pain episodes. I’m currently having great success with tweaking my diet with ZOE and some the Gluecose Goddess dietary hacks.
Wishing the best
Pappolla MA, Manchikanti L, Candido KD, Grieg N, Seffinger M, Ahmed F, Fang X, Andersen C, Trescot AM. Insulin Resistance is Associated with Central Pain in Patients with Fibromyalgia. Pain Physician. 2021 Mar;24(2):175-184. PMID: 33740353; PMCID: PMC10450756.
https://pubmed.ncbi.nlm.nih.gov/33740353/#:~:text=Insulin%20Resistance%20is%20Associated%20with%20Central%20Pain%20in%20Patients%20with%20Fibromyalgia