Thanks for all the information--after getting off the Reglan, were you able to restore the functions compromised? I'm so sorry you went through that. I had a client once who also lost her career, I think due to Reglan. Without divulging her name, I mentioned her difficulty to a friend, a clinical psychologist. There was a drug that should have been given concurrently to prevent these symptoms. I don't recall what it was, but will get back on the net. This is probably not the place to go after information I should get for myself. My sister has had some better days--keeping down food, no vomiting, diarrhea much reduced--a week into the treatment with reglan, zofran, and the nitozoxanide. The nitozoxaanide course ends in a few days, which is known for gastric upset, and I'm hoping to drop the reglan. She will have to make the case to her doctors. Will revisit this in a couple days. Thanks again for your thoughtful response.