1. < Polymyalgia Rheumatica (PMR)

Are you taking Plaquenil (Hydroxychloroquine) for PMR?

Posted by wilckdds @wilckdds, Sep 21, 2023

I was given Plaquenil about 4 weeks ago. 400mg once a day. I was told that it could take 6-8 weeks for it to work. I am feeling a bit better and can get out of bed easier than before I started taking it.

The pain in my legs and thighs has lessened for most of the day but I do take an occasional extra strength Tylenol some mornings. Right now my biggest problem is the pain in both of my biceps with right to left movement which does not letup at all. I have tried getting back to playing playing pickleball and my legs are no problem, but swinging the paddle is very painful.

I would love to hear from anyone also on Plaquenil about how long that you have been on it, is it working and what type and locations of pain you have, or if you have no pain.

Thanks.

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menetski4 | @menetski4 | Mar 30 9:34am

I was taking Hydroxychloroquine 20mg for treatment of non-ankylosing spondyloarthropathy (na-Spa) for about 3months. Then I developed PMR. Has anyone else ever experienced this sequence of events? Could this be an adverse reaction of Hydroxychloroquine?

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1 reply
reets70 | @reets70 | Mar 31 5:56am
In reply to @menetski4 "I was taking Hydroxychloroquine 20mg for treatment of non-ankylosing spondyloarthropathy (na-Spa) for about 3months. Then I..." + (show)
@menetski4

I was taking Hydroxychloroquine 20mg for treatment of non-ankylosing spondyloarthropathy (na-Spa) for about 3months. Then I developed PMR. Has anyone else ever experienced this sequence of events? Could this be an adverse reaction of Hydroxychloroquine?

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I have never had a negative reaction to Hydroxychloroquine and I’ve been on it for 18 years. I too had PMR last year, and I have never been pain free. I am much better after a six month course of methylprednisolone but never completely cured.

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jrp11948 | @jrp11948 | Mar 31 8:14am

I was diagnosed with PMR on January 12, so I’m new to this. Have been on prednisone since then, was doing some good, but it would take till mid afternoon before I as pain free. The doc added Plaquenil at 30 days, so I’ve been on it for about 2 weeks and I believe it has helped. Most of the pain is gone by late morning and what pain I have early in the morning is much less. I’m just starting to taper the prednisone, started at 10 mg, went to 15, now I’m back to 10, soon to be 9.
So far I’m happy with the Plaquenil.

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