I don't know if this is helpful as I take one 100 mg Metoprolol every morning. My cardiologist switched me from 50 mg at night and 50 mg in the morning to one 100 mg in the morning when I started Camzyos. I am not on any other heart medication. Everyone starts at 5 mg and gets 35 capsules. I have been on camzyos for 10 months. Initially, I was changed from 5 mg of camzyos to 2.5 after 30 days . In the course of the 10 months I was switched back to 5 mg (in December) and now have been switched to a 10 mg dose. You will have your echos every month for three months. Basically, you cardiologist will be looking at your LVOT pressure gradient. Mine has changed over the 10 months being on Camzyos which is why my dose has changed. Let your cardiologist know if you have any symptoms such as fatigue or anything else that concerns you.