What is doc looking for with a Bone Marrow Biopsy?

I am not sure what question, I should be asking however has anyone ever had to have two bone marrow biopsies done? My daughter is at the Mayo Clinic in Jacksonville as we speak and they are telling her they didn't get further enough to get the bone marrow biopsies I'm confused why would you have taken one if you don't get enough bone marrow, and my daughter is skin to bone there is no fat in her body since this leukemia and cancer diagnosis

I wanted to add because of my genetic mutation and the findings from the bone marrow biopsy, I have been on blood number watch for 6 months. Knowing what they found leads to leukemia. I was on the low to med in my possible road to develop leukemia.
But, I have Brca2/ Her2+ from my breast cancer and a 2nd mutation. Do I want to roll the dice in the hopes leukemia does not hit my door? No. I went on the bone marrow list"Be a Match" and a perfect match was found by December. I have a transplant April 9th.
Thankfully most bone marrow biopsies will reveal less than what mine did. I was a platelet donor for 25 years. In the low 300's most of those years. Now it was last sitting at 98 and dropping ever few weeks. My white cells at 280 or so. Dropping too.
That is what lead me to hematology and finding my TP53 was off.

Best wishes for a successful procedure on April 9th.

@tperez3333, I'd like to add my welcome. It can be hard to know what questions to ask when you don't know what you don't know. Remember, no question is a dumb question.

I would start by asking your daughter's cancer team questions like:
- Why were you not able to get a successful sample during the bone marrow biopsy?
- What can be done to ensure success at the next biopsy?
- Is there an alternative that can be used if biopsy is not possible?
- What are the next steps?
- What else do I need to know?

Has your daughter had the second biopsy since you posted? How is she doing? How are you doing?

Hi all, only the last two questions are relevant. I too had a bone marrow biopsy and was told my bone marrow was dry so there was no fluid to draw for testing. I was still diagnosed and started on weekly injections. The alternative is stem cell transplant but I don't want to put myself through that, according to what was described to me by the expert.
From what the inquirer described about their daughter, her doctor must already suspect the cause and wanted to verify. Need to discuss with him/her.
Not a pleasant state of affairs. Prayers for restoration.

By the way, I just received information about sleep from Mayo, while I have been waiting for over a year to hear back on consultation for my myelofibrosis condition.
Any help?