Pruney fingertips? Hashimotos?

Hi I noticed once I got sjogrens related dysautonomia/POTS, small fiber neuropathy and Raynaud's my fingertips became pruney.

Perfect description of my fingers...thought it was from small fiber neuropathy only. Do you know what exactly causes it? Thanks

This is an extremely off-topic question, but did you notice your energy levels improving when you started the B12??

I'm going through a similar situation. Can you tell me if you feel any discomfort, pain or pulling feeling associated to the wrinkling?
My hands swell, wrinkle and I literally can't make a fist. I never had this issue until I had heavy metal poisoning. It's gotten so bad I can't write, type long, or hold my phone without my hands ending up in major pain.
I'm so discouraged because it continues to get worse and all they can tell me is it's some kind of histamine reaction.

Fingertips like yours are often associated with Raynaud’s phenomenon, spasms in the small arteries that decrease blood’s flow to the fingers. This causes the fingers and sometimes feet and toes to turn bluish purple, dead white or red, sometimes all 3 colors in patches. Raynauds is associated with autoimmune disorders such as lupus and scleroderma. It’s brought on by cold and stress or just happens intermittently. If you have these color changes, take a picture to show your Dr. It’s important to keep hands warm, avoid contact with cold things like water, frozen foods, etc. And do not smoke. Medication like calcium channel blockers can help if the condition is painful. I would ask your Dr to do some screening for autoimmune diseases just to rule that out.

Swelling of the hand’s combined with Raynauds color changes and wrinkled fingers can be a sign of mixed connective tissue disease (MCTD), an overlap autoimmune disorder with features of lupus, scleroderma and polymyositis. This is characterized by high RNP antibodies in the blood as well as other autoimmune antibodies. A rheumatologist is the appropriate physician to consult to rule this out. I hope you get help with this. It’s very uncomfortable but can be treated to reduce symptoms.

This is a great post and I was just talking about my fingers this morning. I'm new to peripheral neuropathy and among the many symptoms are my wrinkly fingers which feel like they've been oin a bucket of water and the fingers turning a variety of colours. I know what Raynauds is but nothing really about it. So thank you for suggesting that this be followed up by a Rheumatologist. Much appreciated and glad to know I'm not the only one going through this.

@hasmig1 Welcome to Mayo Clinic Connects!I’m so glad you found the site! And it sounds like you’re glad, too. When were you diagnosed with peripheral neuropathy? There are many good discussion group that you may find helpful and I see that you have found it already!
Can I ask how you found Connect?

Hi, Sorry to hear that you're experiencing this issue with your fingertips. * I'm not a doctor but can tell you what my experience has been. I have Hashimoto's also & 3 other Auto immune disorders. I noticed that when taking valacyclovir for my EBV-Epstein Barr Virus my fingertips did the same. It was a dehydration issue. Apparently I needed to really ramp up my water intake with this med. You may have a med. or supplement or a combination of them that is causing this major dehydration. Diet can play a role too, like too much salt intake. Environment also, like excessive heat or possibly working out and not replacing fluids lost, or fever. Have you changed something in any of these areas ? Have you tried Gatorade or Pedialyte to rehydrate ? * If you have high blood pressure be careful with the Gatorade. You could also try to add a banana into your diet every day for added potassium. Bananas are great if you're getting muscle cramps due to dehydration. * Most importantly, bring this up with your doctor.

Hi Sheliez, I 'm 72 and have not just pruney finger but hands. I've looked it up and one reason given is that is just part of getting older...good luck !