I took anastrozole for three and a half months. After the first 90-day prescription I was fine and was greatly encouraged by the shrinkage of my tumor and my smaller tumors in the left breast. It was so shocking that they shrink so much and I was thrilled. Then I went to a prescription for the next 90 days and that's when everything went South. I will be getting a lumpectomy in another month and a half and I will not be getting any radiation or chemo. I am 78. There is controversy and clinical trials about giving women over 70 radiation. They do not find it effective for whatever reason.