Yes, I am very familiar with this trial. RMC-6236 is a unique drug compound designed to be a “pan”-KRAS targeted therapy meaning it is potentially capable to target several of the KRAS variants-not just a single one.

Here is the link to the trial descriptor, all the sites currently recruiting and the contact phone and e-mail of the trial sponsor. Look for a site near you that indicates recruitment is open. Do a Google search of the institution and for the link to clinical trials. Once in that section of the facilities’ website where all trials are listed, search for RMC-6236. It will give you the contact info for the principal investigator (P.I.) and the clinical trial nurse coordinator. If you have difficulty finding this information, contact the Pancreatic Cancer Action Network (PanCan.org) at 877.272.6226, M-F, 7:00am-5:00pm PT. Speak to a case manager who can look up contact info for the RMC-6236 clinical trial.

There is a lot of interest in this trial because 90% of pancreatic cancers are linked to a KRAS somatic mutation. That means each site likely will meet their accrual quota quickly. I suggest you obtain your complete medical records and follow through quickly if you are interested in participating in this clinical trial. They key pieces of information a P.I. will need to determine eligibility are: Cellular Pathology report confirming specific diagnosis, a surgical pathology report if surgery was performed, Radiologist interpretations of current and prior imaging (CT or MRI), copies on CD or the imaging, current blood chemistry and hematology reports. Chemotherapy log detailed administration of each chemo cycles, drugs used and concentrations. Most of this will be available on your patient portal and can be downloaded and sent as a pdf file. If you were not requesting copies of your imaging at the time they were done, then you will need to contact the medical records department to obtain them. The chemo administration log likely will not be in the patient portal. Contact your N.P. who can obtain that file which is usually in the form of an Excel spread sheet.