First started with anastrozole but had a reaction (itchy all over) so was switched to letrozole. I initially experienced hot flashes and stiffness in my hips after sitting for a while, but both resolved on their own. Thought I might be losing more hair than usual so doctor recommended an inexpensive hair, skin & nail supplement and that problem was solved. Otherwise, I’m thankful to be pretty much symptom free. Supplements I’ve always taken that may be helping me: Estroven (rhubarb root extract) for hot flashes and a triple action joint health supplement from Costco. I also upped my calcium intake, walk daily and do a weight-bearing workout once a week.