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@sallyj2
https://www.ncbi.nim.nih.gov/pmc/articled/PMC7862223/

2021 article: Menaquinone 4 increases plasma lipid levels in hyoetcholesterolemic mice.
Study by: Weisell, Ruotsalsinen, et al

FYI, I am not a mouse and mine increased substantially. Three months after stopping, it went back down. Hoping estrogen lowers it further.

I guess my caution would be that even supplements have effects and side effects and everyone is different. I just happened to stumble on this, knowing it was the only change I had made. Another good reason to add things one at a time when possible,

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Replies to "HTTPS://www.ncbi.nim.nih.gov/pmc/articled/PMC7862223/ 2021 article: Menaquinone 4 increases plasma lipid levels in hyoetcholesterolemic mice. Study by: Weisell, Ruotsalsinen,..."

Hi @sallyj2, while studies in mice shouldn't be directly extrapolated to human, what you have experienced is interesting. LP-a is said to be genetically determined by both copies of parents' genes (they call it co-dorminance) and not affected by diet, exercise or drugs. There is a slight increase in postmenopausal women. Most people just need one test during their lifetime. Mine was done twice by accident, the difference was 60%. Since both of my results are at low end, 10 and 16nmol/L, they didn't trigger my nerve. The distributions of LPa among the population is very skewed. If you are at low end, the difference between tests might be inherent test errors. Did you go to the same lab? The results are also expressed in different units, nmol/L vs mg/L. Check and see if both of your results used the same units.

Thanks for the link. I am mystified about my lp(a) reading. It increased by 50% in a few months. All other values are good.

I'm sorry as I don't understand a lot of the medical terminology as I have
no access to much out here where I live and no medical care anymore because
lack of transportation and circumstances put me in a bad way. It's serious,
and I can't respond to emails and read the posts as I'd like to. Thank you
for responding and for your feedback. Pamela