My CTX before Tymlos was 324 but not fasting, which raises it. After 18 months on Tymlos, 165 then 186 last summer, and after one month Evenity 145. I just did it again after 3rd Evenity.

Baseline P1NP was 54, 18 months after Tymlos started it was 40, and after one month of Evenity it was 33 (sorry I had a lapse there and put that as my CTX!). I just did that again mid-month because doc said the last one was at day 30 of Evenity so not at peak action.

I was lazy...loggging in to my portal is a pain! Now I see how low your CTX is! My P1NP is puzzling to me and my docs. It may be that Tymlos stopped working by 18 months, according to docs, so that is reasonable. But after Evenity I expected a higher value.

Anyway... sorry for tangent, just wanted to correct previous post. Your CTX is indeed low and it would seem that is from the alendronate-? You would seem to be avoiding rebound quite strongly!? (I put reference range for CTX for my lab, at the bottom of this) This is good news for others...

ps I am taking a little more calcium with Evenity since it can cause low calcium; Tymlos makes it higher for a short time

148-967 (18-29 y)
150-635 (30-39 y)
131-670 (40-49 y)
183-1060 (50-59 y)
171-970 (60-69 y)
152-858 (>70 y)
136-689 (Premenopausal)
177-1015 (Postmenopausal)
Flagging is based on the
age-specific reference
interval and not menopausal
status.