I have had Polycythemia Vera (PV) for 6 years now. No other symptoms before diagnose other than a sky-high platelet result on a routine blood test. I was started on Hydrea 500mg 2x a time day. Platelets under control. After 5 years I now just take one 500mg Hydrea in the morning. I never had a phlebotomy or a blood marrow test which seems strange as every person who has PV on this site is talking about having a phlebotomy occasionally. I don't have many side effects other than getting verry tired at about 5 pm every day. I plan all of my studying and brain work early in the day. I go to my gymnasium 3x a week and am very involved with my veteran organizations. I just turned 65 and plan to be around for a long time. I wish the best for you. J.