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How long do the side effects of Lupron/Eligard last?
This Monday I am getting my number 3 and last injection of 6 month duration Eligard/Lupron. This is after 39 Proton Beam sessions which began 3 months after I was started on the 18 month protocol of ADT treatment.
My question is for those who have gone this route, how long after this last injection will I begin to get some relief from the medication? The hot flashes and perspiration seem to be the most obvious and prevalent side effect. Weight gain around the waistline and shrinkage of other body parts is noticeable but does not affect comfort as the perspiration accompanied by the hot flashes. I am really bothering my wife with the roller coaster movement of the air conditioning thermostat, up and down throughout the day...and night. lol
As I write this I get my last injection tomorrow and six months since the 2nd injection the hot flashes feel as bad as they did 6 months ago.
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Thank you all for sharing your experiences. I'm hoping for short term side effects. Original PSA was 15 and had undergone a prostectomy 18 months ago, PSA was undetectable until now. It had risen to (0.4). Thankfully my PET scan came back clear for mestasis. Going through beam radiation therapy (6 days in of 38 treatments). Doc recommended 1 shot of Lupron (supposedly lasts 3 months). I'm not looking forward to side effects of either treatment.
My Salvage Tx was IMRT radiation 37 txs together with 4 mos ADT. I took Orgovyx.
Side effects (SEs) for me were moderate but manageable.
Difficult to differentiate between causes.
Radiation Proctitis was a SE for me, and it cleared 2 - 4 wks post radiation.
ADT caused fatigue, minor hot flushes, mental fog. I describe it as all the issues of a 73 yr old exacerbated.
All SEs abated substantially about 4 mos after ADT completed, except some residual mid afternoon fatigue, when my recliner looks particularly inviting.
Not an expert, but I think that Lupron comes in 1, 3 & 6 mos injections.
SPPORT trial supports 4 - 6 month short term ADT together with radiation to whole pelvic region (WPRT).
Good news is that my 2 PSA tests following salvage tx have been undetectable.
Short answer to the Q initially posted: Too long!
Good luck with your treatments.
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4 Reactions@socoldad, just thought I'd check in. How are you doing? How is treatment going?
This is the best question for feedback..in my case I had Lupron for 2yrs and now on 7 month holiday.. my psa is undetectable…BUT still have sweats at night..all good👍
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1 ReactionThank you for reaching out to me. I am doing as well as can be expected I guess. My daily routine has changed because of fatigue but napping is supposed to be good for me. I am also at the mid point of my radiation therapy and the diarrhea seems to be my worst side effect. It's beginning to effect my appetite.
Thank you for your reply. Your description of all the issues of a 73 year old exacerbated is on point. At the half way point of my radiation therapy and I am starting to feel that exacerbation.