I have run the gamut of medications for restless leg syndrome (RLS) over the past 25 years, and most of them worked for a period of time and then stopped working or 'rebounded' and created increased symptoms of RLS after a period of time. As I age, my restless leg severity increases exponentially also. I also have fibromyalgia and chronic fatigue (diagnosed by Fibromyalgia Department at Mayo) so when I don't get enough sleep, those issues, along with a back that has had cervical and lumbar surgeries, flare up and are more painful also. Requip worked for about nine years, and then I needed to increase dosage: at first every two-three months, and then it was every two weeks. Each time, I experienced nausea/vomiting, dizziness and sometimes fainting, and a severe headache the next morning. I have been seeing a Sleep Center doctor at Mayo, and she is great, but we have been struggling to find something that works more effectively than Gabapentin which creates issues with my memory . . . when I was taking a higher dose of 1200 mg daily, I was afraid I was developing dementia my thinking was so skewed. Lower doses, 600 mg work better. I recently asked about Neupro which I heard about from a friend who knew someone who had great success with it. However, it too has side effects; same as Requip with the nausea/vomiting, dizziness/fainting, and headache at first dose . . . . but memory issues are somewhat different. With Neupro, at numerous intervals during the day, it will feel like someone dropped a blank box in my brain, and when I try to recall something I know that I know, it just isn't there. It's been a month and a half of taking Neupro, and for a period of four years, I was getting 1 1/2 - 2 1/2 hours of sleep per night sometimes in 15-20 minute intervals with a 6-7 hour night every ten days to two weeks. Needless to say I was a walking zombie. I am wondering if anyone else is taking Neupro and what their experiences are?