@gently I once read that true compliance is telling your doc what you are doing!

I think it is different if you tell your doctor you are on two clicks vs telling your doctor that you could not tolerate 8 clicks but managed to work your way up to 6 (which is therapeutic). Key though is trying the prescribed dose first, or at least half of it.

My doc not only supports ramping up but based on my finally getting on a medication after years of trying, now suggests it to patients having similar problems. If I hadn't told him what I was doing, he might not have changed his practice in this way.

@gently, I’m new to Mayo Clinic Connect and I can’t imagine navigating through osteoporosis without it. Specifically - windyshores is the reason I was able to start Tymlos without so much anxiety, even though I did not start with a full dose but at 2 clicks. My PCP was against it at first as “all my other patients are fine with full dose”. I think she was not aware this was even possible, so now she does and maybe other patients will benefit. We have “butt heads” on other issues in the past and guessing there are notes in my chart that I’m a “difficult” patient….but we have to be our own advocate. I thank you for all your comments and support, I know I can’t get through this alone.