Hello @manuelpo. In my case the hiccups were very minor, and not the type you mentioned. When first on the drug at 5mg, I had 2 or 3 one-day events in which it felt like all of my normal oHCM symptoms were back but by the next day those symptoms were completely gone again. In the first couple weeks at 10mg, I had 2 brief episodes (a minute or two each) in which I experienced terrible, full-body joint pain. that came out of nowhere and then disappeared just as quickly. It may have had nothing at all to do with Camzyos. I've been charting my blood pressure almost daily since before starting Camzyos and it hasn't changed appreciably. Other than those few incidents I have have no negative side effects whatsoever. Best wishes for success - I hope you have good results!