Should I be worried about my MGUS diagnosis and my M Spike rising?

Posted by rhody89 @rhody89, Dec 5, 2023

I’m a 33 year old male and I was diagnosed with MGUS at the beginning of this year after recurring fevers and body aches the year before, with no one around me getting sick. I went to the doctors in the beginning of 2022 and they did a full blood panel and it came back with an abnormal protein in my blood and it came back as monoclonal gammopathy with IgG Kappa. It was very low at .16 g/dl. I went to see a blood specialist and at first they shrugged it off and said it could just be autoimmune. I decided to then get a second opinion and was told to go to Boston to see a specialist who just deals with multiple myeloma patients and studies younger patients.

Since seeing a specialist in Boston my protein spike stayed relatively the same and went to .19 and .25 g/dl. I just got tested last week and I saw it went to .68 g/dl. Now I know it’s still small and has to be above 3 or 10g/dl to be more serious. My doctor said he’s not worried and that it’s a 1% chance every year to become multiple myeloma, which is a very small odd.

Should I be worried about the small jump in my spike? All my other labs were normal, with just a slight elevated LDH.

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Hubby discussed his latest labs with his doctor today. She is not concerned with his MSpike rising from 1.0 to 1.3. It was 1.2 before that, so apparently it can go down as well as up. Said to get re-tested in 6 months.

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