I'm a scientific sample of one (!), and I'm not any sort of medical professional, so please take my response with all the appropriate caution. I was diagnosed in April 2023 as stage 4 because my surgeon saw flat lesions during my staging laparoscopy. Since then, I've asked my oncologist about various treatments besides chemo. Examples: HIPEC (the heated intraperitoneal chemo), high-dose radiation, proton beam radiation, surgery. In every instance, my oncologist said no, they're not for me. If I think about it, it seems very logical. For example, there's no guarantee that surgery would catch and remove every lesion and every cell. Radiation and proton beam therapy are so targeted that there's no way they could hit every affected area. The HIPEC treatment would make me extremely sick, he said. And so on. So I believe what he's telling me is correct in my case. That said, I urge you to ask and research and consider all your options, because you may be luckier than I am. I'm curious--what kind of injections would go into the lesions? What is the drug?

They might be able to apply chemo directly to your liver with a pump:
https://www.ohsu.edu/knight-cancer-institute/hepatic-arterial-infusion-hai#:~:text=In%20HAI%2C%20doctors%20place%20a,which%20means%20fewer%20side%20effects.

They might also be able to apply radiation directly with a patch like the Civa Sheet:
https://civatechoncology.com/civasheet/

Please share if your PA or oncologists can provide any insights on these!