I have been taking the big three antibiotics for two years. When I didn’t convert to negative the dr added arikayce. I took it 6 months and converted. Have continued taking it for 1 year after converting. I finish in June. I’ve had no side effects. The sore throat goes away after the first several doses. I take it religiously with my antibiotics and believe it’s the reason I cleared the MAC. I worry when I finish the regime that I will reinfect but that’s MAC