Regarding curcumin, it is not readily absorbed in the GI tract so best to take "bioavailable" curcumin that has been changed to increase absorption, or curcumin with black pepper (the peperine increases absorption but also intestinal permeability [a problem is someone has leaky gut from celiac or other]). The curcumin is antiinflammatory and research suggests is decreases TNF (tumor growth). I take a couple of pills/day for MGUS (8 years). No symptoms other than minor balance (I do PT and balance half dome for the peripheral neuropathy).