Based on my experience, there is little need to be patient with the settings for CPAP. It's either right for you, or it isn't. You'll know it over three blissful nights if it's right, or three longer ones if it ain't.

Most prescriptions, for some unfathomable reason in the 21st century, start with the expiration pressure at 4 or 5. That's too low for about 75% of all patients. Or, their EPR (Expiration Pressure Relief) is too much or too little. Further, quite a few of us develop what is called 'treatment emergent central apnea'. Our diagnosis is for obstructive apnea, meaning the air passages are pinched or actually blocked much of the time. But, when we commence treatment, particularly if our EPR is set too high, we begin to have 'open airway' show up on the ResMed machines' readouts next day. Sometimes this phenomenon is self-limiting, but sometimes changes have to be made to the original prescription. Open airway is ResMed's characterization of the machine getting no feedback, as if your airway is open, but you're not inhaling or exhaling. That is what a central apnea is...you stop breathing, sometimes for extended periods as long as 30 seconds.
There is a lot more, and its quite complicated, and it really behooves all of us users of PAP machines to learn what we have, how best to treat it, and then how to adjust our machines so that they help us to sleep well.