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Initial blood tests to ask for ?

Osteoporosis & Bone Health | Last Active: Mar 11 5:27am | Replies (54)

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@windyshores

So timing of blood test bone markers is important. Not only should CTX be done early in the morning, fasting, but these tests should be done when treatment is peaking. For Evenity, the P1NP needs to be done on day 14, according to my doc, when the drug (and side effects) are peaking. I would actually do day 12. My P1NP was lower than expected after my first injections but the test was done at the end of the first month of treatment.

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Replies to "So timing of blood test bone markers is important. Not only should CTX be done early..."

Hi @windyshores I read that for evenity, the steady state is reached at 3 mo. There was a phase 1 study showed that at end of 3mo, the bone marker p1np showed increase. Also at the end of 3mo, bmd increased 5.3% in L spine and 2.3% at total hip with statistical significance in 785 subjects. You will have a few more shots, right? Your p1np might show a change after 3 mo.

Is getting a baseline important in addition to when the treatment is peaking? Thanks.