Tips on minimizing withdrawal symptoms from Effexor (aka Venlafaxine)

Posted by richyrich @richyrich, Nov 2, 2016

I have been taking Effexor/Venlafaxine for years and tried to get off it a few times but each time I try to give up the chemical withdrawal symptoms are a horror story and I give up giving up. Anyone got any tips or tried and tested strategies? Thank you

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in reply to @njoys I am profoundly sorry to learn about your suffering, and agree that the doses of medication that were initially prescribed seem high. Can you consult with your pharmacist in this regard, or at least in terms of the Effexor. I too am tapering off of Effexor XR, now down to 37.5 mg capsules, making it difficult to measure out just the right amount without suffering any of the horrible side effects of doing so. I am fairly certain my pharmacist was correct when she told me that this particular medication is harder than heroin to get off of, and that it will take me at least 6 months to taper off of the 37.5 mg dosage that I have been on for at least 6 months. Everytime I try to taper down, I end up with horrific nightmares and an overall sense of feeling unwell. Your comment about your depression caught my attention because while recently talking to a psychologist we both concluded that my depression was situational and she did not think I had a chemical imbalance. She is also a MD by the way. In any event, I hope that you are able to recover from this affliction sooner rather than later.
Godspeed

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Profile picture for frances007 @frances007

in reply to @njoys I am profoundly sorry to learn about your suffering, and agree that the doses of medication that were initially prescribed seem high. Can you consult with your pharmacist in this regard, or at least in terms of the Effexor. I too am tapering off of Effexor XR, now down to 37.5 mg capsules, making it difficult to measure out just the right amount without suffering any of the horrible side effects of doing so. I am fairly certain my pharmacist was correct when she told me that this particular medication is harder than heroin to get off of, and that it will take me at least 6 months to taper off of the 37.5 mg dosage that I have been on for at least 6 months. Everytime I try to taper down, I end up with horrific nightmares and an overall sense of feeling unwell. Your comment about your depression caught my attention because while recently talking to a psychologist we both concluded that my depression was situational and she did not think I had a chemical imbalance. She is also a MD by the way. In any event, I hope that you are able to recover from this affliction sooner rather than later.
Godspeed

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I believe your post is in reply to @dfb
I sympathize with your horrific nightmares and dfb's extreme anxiety, as I shared those withdrawal symptoms. I am back up to 50 mg per day (25 mg immediate release tablet am & pm), and hope to remain stable awhile longer before trying to discontinue again.
May I ask how many beads you are removing from the 37.5 mg capsules in your attempt to taper? (with apologies if it's a repeat question).

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Profile picture for wendyw @wendyw

My son has taken his prescription to a compounding pharmacy who is reducing to dose so he can slowly taper off the 37.5. He is now a week into having the 18.5 mg and it’s been much better than when he tried to stop the 37.5. His plan is to do this for another week, then go down to 9 mg for a few weeks. It seems everyone reacts differently to the withdrawals but this tapering is better for him. I spoke to Pfizer yesterday and suggested the make weaning off dosages too!

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How can I get the 18.5 I am on 35.5 I tried to take it every other day but the side effects from not taking it is bad I need help please

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Morning,

Let me begin by saying I feel all your pain. I. Am 78. My journey of addiction began when my 9 years older brother got me drunk at age 9. This would lead to a binge drinker addiction that moved from beer to scotch, gin and tonics, martinis, gibsons, and finally straight gin (hold the vegetables). I had my last binge episode around 1994. After. That episode I stopped drinking cold turkey. Along this life adventure I found myself on Zoloft. I began Zoloft at a point in my life where I had one through a divorce, endured the absence of my two beautiful daughters. I would be on Zoloft for approximately 20 years. Around 2012 my internist added in Venlafaxine. Around the beginning of the Pandemic when my current wife and love of my life found herself being treated for pancreatic cancer I would go through withdrawal from Zoloft. So now I am left on one (1) 70 mg of Venlafaxine per day.

I am about to launch myself through the doors of final psychiatric adventure. You see my wonderful soul mate still has to endure my erratic mood disorders. I need some help from my friends at the Mayo Clinic. What should I do? I will do anything to help my partner for life. You see she saved my life when she took me on 30 years ago.

Any advice, I hope?

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Profile picture for kareemscott814 @kareemscott814

How can I get the 18.5 I am on 35.5 I tried to take it every other day but the side effects from not taking it is bad I need help please

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Effexor is available in 25 and 50 mg tablets, and in 37.5 and 75 mg capsules. As you have discovered, taking the drug every other day does not work. If you are trying to decrease the dosage in order to successfully discontinue the medication, then what is recommended (according to my online research) is lowering the dosage no more than 5-10% at a time, and remaining at that dose until you feel "normal." Once you've been stable for a month or two or however long it takes at that dose, then the next step is to decrease another 5-10%, etc, etc, etc. Because the pharmaceutical companies do not make Effexor available to us here in the US in decreasing doses, one has to manage this oneself or seek the aid of a compounding pharmacy to do it for you. To do it yourself, you shave a bit off a tablet or remove beads from a capsule. It is not an easy process, and shame on pharmaceutical companies for creating a dependency on a drug with no easy way to discontinue it. Withdrawal is hell. It is tragic to see how many of us are suffering from side effects and withdrawal effects of Effexor.

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Profile picture for njoys @njoys

Effexor is available in 25 and 50 mg tablets, and in 37.5 and 75 mg capsules. As you have discovered, taking the drug every other day does not work. If you are trying to decrease the dosage in order to successfully discontinue the medication, then what is recommended (according to my online research) is lowering the dosage no more than 5-10% at a time, and remaining at that dose until you feel "normal." Once you've been stable for a month or two or however long it takes at that dose, then the next step is to decrease another 5-10%, etc, etc, etc. Because the pharmaceutical companies do not make Effexor available to us here in the US in decreasing doses, one has to manage this oneself or seek the aid of a compounding pharmacy to do it for you. To do it yourself, you shave a bit off a tablet or remove beads from a capsule. It is not an easy process, and shame on pharmaceutical companies for creating a dependency on a drug with no easy way to discontinue it. Withdrawal is hell. It is tragic to see how many of us are suffering from side effects and withdrawal effects of Effexor.

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Whole simple foods, no chemicals! Deep Darth Vader breathing. Water. A daily routine. Benzo withdrawal is the same. Horrible, horrendous. My thoughts and prayers are with you. Hope is on the other side. The saying is "The only way out is through" and that is true. You are a warrior. Stay strong. You have this! 🙏🏻💪🏻🫶🏻

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Profile picture for Mort @kuma

Morning,

Let me begin by saying I feel all your pain. I. Am 78. My journey of addiction began when my 9 years older brother got me drunk at age 9. This would lead to a binge drinker addiction that moved from beer to scotch, gin and tonics, martinis, gibsons, and finally straight gin (hold the vegetables). I had my last binge episode around 1994. After. That episode I stopped drinking cold turkey. Along this life adventure I found myself on Zoloft. I began Zoloft at a point in my life where I had one through a divorce, endured the absence of my two beautiful daughters. I would be on Zoloft for approximately 20 years. Around 2012 my internist added in Venlafaxine. Around the beginning of the Pandemic when my current wife and love of my life found herself being treated for pancreatic cancer I would go through withdrawal from Zoloft. So now I am left on one (1) 70 mg of Venlafaxine per day.

I am about to launch myself through the doors of final psychiatric adventure. You see my wonderful soul mate still has to endure my erratic mood disorders. I need some help from my friends at the Mayo Clinic. What should I do? I will do anything to help my partner for life. You see she saved my life when she took me on 30 years ago.

Any advice, I hope?

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Hi @kuma, You'll notice that I removed your email address. Connect is a public forum. We recommend sharing personal contact information using the secure private message function.

I might also add that by sharing here in the forum, you are connecting with several people where all can benefit from group support.

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Profile picture for Colleen Young, Connect Director @colleenyoung

Hi @kuma, You'll notice that I removed your email address. Connect is a public forum. We recommend sharing personal contact information using the secure private message function.

I might also add that by sharing here in the forum, you are connecting with several people where all can benefit from group support.

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Thank you so much. 🙏🏻

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Profile picture for Colleen Young, Connect Director @colleenyoung

Hi @kuma, You'll notice that I removed your email address. Connect is a public forum. We recommend sharing personal contact information using the secure private message function.

I might also add that by sharing here in the forum, you are connecting with several people where all can benefit from group support.

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So good to have this message from you. For some reason I thought you had retired. Glad to see you are still involved. You bring a wealth of knowledge and experience.

Namaste 🙏🏻

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Glottis breathing. Amazing way to enervate the vagus nerve. Relaxes the whole body. Sounds like Darth Vader. 🙏🏻🌞

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