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@sunporch

For everyone who says they are tired, how are you Ferritin and Iron Panel levels? If these are low you may need to take an iron supplement and that will help with the fatigue. Mine got so low that I was anemic, but before doing anything drastic, they advised me to take a supplement, which I did, and I felt better after a while. My iron level also went up to the point that it was high and I stopped taking the supplement. So I've been good for a while now. Monday is more blood work and a visit with the hematologist so I'll find out where I'm at as far as my iron level.

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I have ET/Jak2. Low iron but I am not anemic. The fatigue did not start until I was on HU, 500 mg, 2x week. I also went off of hrt for hot flashes due to concerns about clotting and strokes. I was on hrt for 20 years. Now, on HU, 500 mg, is 3x a week. The hot flashes are hourly and disturb my sleep. I am taking Evening Primrose Oil several times per day for hot flashes, but not seeing improvement. My blood work is better with the HU and iron supplement but the fatigue is interrupting my life.