@oooanooo, Welcome to Connect. Before my own liver and kidney transplant, I had the tiredness/fatigue, couldn't walk far, no appetite, etc. These are some of the symptoms that can occur with liver disease and advanced cirrhosis.
Here is some information about liver disease if this is new to you.
- Liver Disease
https://www.mayoclinic.org/diseases-conditions/liver-problems/symptoms-causes/syc-20374502
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Here is a Connect discussion with members who have experience with liver cancer HCC
- Anyone waiting for liver transplant and diagnosed with liver cancer?
https://connect.mayoclinic.org/discussion/liver-transplant-6/
@oooanooo - Where is your brother-in-law in his current need/journey to a possible liver transplant? Has he been treated for the HCC and Hep B?

@katebw Do you have any information about Hep B before liver transplant?