My endocrinologist failed to order baseline BTMs. I took alendronate for 1.5 years, a 4 month bisphosphonate holiday, and then one dose of zoledronic acid in November 2021. My endocrinologist wanted me to have two doses of zoledronic acid, meaning a 2nd one in November 2022, but when I started doing my own research, I began to question if he is really up to speed, and instead of having the 2nd infusion, one year to the day of my one and only zoledronic acid infusion, I had BTMs labs at my request. Of course, since bisphosphonates stay in your system for a long time, there is no way to be 100% certain if the bisphosphonates weren't still affecting my 2022 BTMs, but my gut feeling is I never had elevated bone turnover. Note, I was diagnosed with hypothyroidism in 2017 (currently take 88 mcg of levothyroxine daily) and hypothyroidism can lower bone turnover, which my endocrinologist failed to mention before prescribing bisphosphonates, actually he has never acknowledged this, and which I didn't learn until after I had had the infusion.

I had my BTMs retested in December 2023, a little over two years after my one and only zoledronic acid infusion and my results were as follows:

NTx (urine test): 13

CTx: 130 ( previous test done in 11/2022 result was) 179

P1NP: 33.5

Osteocalcin: 9.4